Mouse Anti-GSTA1 Monoclonal Antibody, Unconjugated, Clone 3G10

  • Mouse Anti-GSTA1 Monoclonal Antibody, Unconjugated, Clone 3G10

    from ProSci
    CatalogueID : 48-847

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Target Gsta1
Species Cross Reactivity Homo sapiens, Mus musculus
Host Species Mus musculus
Target Tag/Conjugate Unconjugated
Applications WB, IHC, IP, IF
Clone Clone 3G10
Target/Molecule Synonym GSTA1, EC, GST2, GSTA1-1, GTH1, H-A, MGC131939
Unit 0.05 mg
Format Purification: Protein G ColumnFormulation: Weight: 50 µg Concentration: 2 mg/ml
Description GST-3G10 recognizes GST (Glutathione S-Transferase), a 26a protein encoded by the parasitic helminth Schistosoma japonicum and used in the pGEX family of GST plasmid expression vectors (Pharmacia) as a fusion protein with foreign proteins. Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.Immunogen: GSTA1 monoclonal antibody was raised against the complete coding region (amino acids 1-425) of GSTA1.Application: GSTA1 antibody can be used for detection of GSTA1 by WB, IP, IF, IHC-parafin (5 µg/ml).Buffer: GSTA1 monoclonal antibody is supplied in PBS, pH 7.4.Storage: GSTA1 monoclonal antibody can be stored at -20ºC for long term storage, and 4ºC for short term storage.
Cite This Product ProSci cat# 48-847 RRID:AB_1946692
Company ProSci, Inc
Type Monoclonal Antibody
Isotype IgG1
Uniprot ID P13745