Mouse Anti-Human GSTP1 Monoclonal Antibody, Unconjugated, Clone 3F2C2

  • Mouse Anti-Human GSTP1 Monoclonal Antibody, Unconjugated, Clone 3F2C2

    from ProSci
    CatalogueID : 32-167

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Target GSTP1
Species Cross Reactivity Homo sapiens
Host Species Mus musculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB, IHC
Clone Clone 3F2C2
Target Species Homo sapiens
Target/Molecule Synonym PI, DFN7, GST3, FAEES3
Unit 0.1 ml
Format Formulation: Ascitic fluid containing 0.03% sodium azide. Purified antibody available at no extra cost.
Description GSTP1 (glutathione-S-transferase, pi 1), also called GST3/DFN7, which is located on chromosome 11q13, is a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. GSTP1 act like a tumor suppressor gene, which when inactivated leads to tumor growth, and the -class glutathione S-transferase is commonly inactivated by somatic CpGisland hypermethylation in cancers of the prostate, liver, and breast. Methylation of regulatory sequences at the GSTP1 gene locus is found in the vast majority (>90%) of prostate carcinomas and is associated with transcriptional down-regulation.GI Number: 2950Immunogen: Ni-NTA purified truncated recombinant GSTP1 expressed in E. Coli strain BL21 (DE3).Application: Western Blot:1:500 - 1:2,000 IHC(P):1:500 - 1:2,000 IHC(F):1:500 - 1:2,000 ELISA:Propose dilution 1:10,000. Determining optimal working dilutions by titration test.Storage: GSTP1 monoclonal antibody can be stored at -20ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product ProSci cat# 32-167 RRID:AB_1946696
Company ProSci, Inc
Type Monoclonal Antibody
Isotype IgG1
Uniprot ID P19157