Rabbit Anti-BAD Polyclonal Antibody, Unconjugated

  • Rabbit Anti-BAD Polyclonal Antibody, Unconjugated

    from ProSci
    CatalogueID : 48-504

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Target BAD
Species Cross Reactivity Mus musculus, Rattus norvegicus
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications WB, IHC
Target/Molecule Synonym BAD, BBC2, BBC6, BCL2L8, bad protein, bcl2-antagonist of cell death
Unit 0.05 mg
Format Purification: Immunoaffinity ChromatographyFormulation: Weight: 50 µg
Description Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain containing pro-apoptotic proteins, such as Bax, Bid, and Bik, form a growing subclass of the Bcl-2 family. Another such protein is the Bcl-2-antagonist of cell death (Bad). Bad regulates apoptosis by forming heterodimers with anti-apoptotic proteins Bcl-2 and Bcl-xL, thereby preventing them from binding with Bax. Bad activity is regulated by its phosphorylation; it is inactivated by kinases such as Akt and MAP kinase and thus promotes cell survival, whereas JNK-induced phosphorylation promotes the apoptotic role of Bad.Specificity: pSer112Immunogen: BAD antibody was raised against amino acids surrounding Serine 112 of BAD. (Human)Application: BAD antibody can be used for detection of BAD by WB, IHC-parafin (20 µg/ml).Buffer: BAD antibody is supplied in PBS, 0.02% sodium azide, 50% glycerol.Storage: BAD antibody can be stored at -70ºC for long term storage, and -20ºC for short term storage.
Cite This Product ProSci cat# 48-504 RRID:AB_1945278
Company ProSci, Inc
Type Polyclonal Antibody
Isotype IgG