Rabbit Anti-Bad Polyclonal Antibody, Unconjugated

  • Rabbit Anti-Bad Polyclonal Antibody, Unconjugated

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    CatalogueID : 3343

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Target BAD
Species Cross Reactivity Rattus norvegicus, Mus musculus, Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB, IHC, IF
Target Species Homo sapiens
Target/Molecule Synonym BAD Antibody: Bcl-2-like 8
Format BAD Antibody is supplied in PBS containing 0.02% sodium azide., Liquid
Concentration 1 mg/mL
NCBI Gene Aliases BCL2L8, BBC2
Description BAD Antibody: Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain containing pro-apoptotic proteins, such as Bax, Bid, and Bik, form a growing subclass of the Bcl-2 family. Another such protein is the Bcl-2-antagonist of cell death (Bad). Bad regulates apoptosis by forming heterodimers with anti-apoptotic proteins Bcl-2 and Bcl-xL, thereby preventing them from binding with Bax. Bad activity is regulated by its phosphorylation; it is inactivated by kinases such as Akt and MAP kinase and thus promotes cell survival, whereas JNK-induced phosphorylation promotes the apoptotic role of Bad
Cite This Product ProSci cat# 3343 RRID:AB_735579
Company ProSci
Type Antibody
Accession Number Q92934
Immunogen Bad antibody was raised against a peptide corresponding to 15 amino acids near the C-terminus of human Bad
Isotype IgG
Molecule Name BAD BCL2-associated agonist of cell death
Clonality Polyclonal