Rabbit Anti-GRASP Polyclonal Antibody, Unconjugated

  • Rabbit Anti-GRASP Polyclonal Antibody, Unconjugated

    from ProSci
    CatalogueID : 50-208
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Target GRASP
Species Cross Reactivity Homo sapiens, Mus musculus, Rattus norvegicus, Canis lupus familiaris, Bos taurus
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications WB
Unit 0.1 ml
Format Purification: Affinity purified
Description PDZ domain-containing proteins, such as PSD-95 and GRIP are thought to play key roles in glutamate receptor plasticity. GRIP-associated proteins (GRASPs) that bind to distinct PDZ domains within GRIP also play key roles in regulation of glutamate receptor function. GRASP-1 is a neuronal rasGEF associated with GRIP and AMPA receptors in vivo (Scannevin and Huganir, 2000). Recent work suggests that GRASP-1 may regulate neuronal ras signaling and contribute to the regulation of AMPA receptor distribution by NMDA receptor activity (Ye et al., 2000).Immunogen: Peptide corresponding to amino acid residues from the C-terminal region of rat GRASP, conjugated to keyhole limpet hemocyanin (KLH).Application: The antibody has been directly tested for reactivity in Western blots with rat tissue. It is anticipated that the antibody will react with bovine, canine, human and mouse based on the fact that these species have 100% homology with the amino acid sequence used as antigen.Positive Control 1: Cat. No. 1473 - Rat Cerebellum LysateBuffer: GRASP antibody is supplied as affinity purified polyclonal antibody, 100 µl in 10 mM HEPES (pH 7.5), 150 mM NaCl, 100 µg per ml BSA and 50% glycerol.Storage: GRASP antibody can be stored at -20ºC and is stable at -20ºC for at least 1 year.
Cite This Product ProSci cat# 50-208 RRID:AB_1946652
Company ProSci, Inc
Type Polyclonal Antibody