Rabbit Anti-Human Caspase-5 Polyclonal Antibody, Unconjugated

  • Rabbit Anti-Human Caspase-5 Polyclonal Antibody, Unconjugated

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    CatalogueID : 3457

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Target CASP5
Species Cross Reactivity Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, ICC, WB, IF
Target Species Homo sapiens
Target/Molecule Synonym Caspase-5 Antibody: ICH-3, ICE rel III
Format Caspase-5 Antibody is supplied in PBS containing 0.02% sodium azide., Liquid
Concentration 1 mg/mL
NCBI Gene Aliases ICEREL-III, ICE(rel)III, MGC141966, ICH-3
Description Caspase-5 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1β and IL-18. Caspase-5 can interact with caspase-1; both are constituents of the NALP1 inflammasome, a complex that can trigger the cleavage of pro-IL-1β. Expression of caspase-5 can be regulated by lipopolysaccharide (LPS) and IFN-gamma
Cite This Product ProSci cat# 3457 RRID:AB_713042
Company ProSci
Type Antibody
Accession Number P51878
Immunogen Caspase-5 antibody was raised against a 14 amino acid synthetic peptide from the center of human Caspase-5
Isotype IgG
Molecule Name CASP5 caspase 5, apoptosis-related cysteine peptidase
Clonality Polyclonal