Rabbit Anti-Human Caspase-6 Polyclonal Antibody, Unconjugated

  • Rabbit Anti-Human Caspase-6 Polyclonal Antibody, Unconjugated

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    CatalogueID : 3471

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Target Casp6
Species Cross Reactivity Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, ICC, WB
Target Species Homo sapiens
Target/Molecule Synonym Caspase-6 Antibody: Mch2
Format Caspase-6 Antibody is supplied in PBS containing 0.02% sodium azide., Liquid
Concentration 1 mg/mL
NCBI Gene Aliases MCH2
Description Caspase-6 Antibody: Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. The apoptotic subfamily can be further divided into initiator caspases, which are activated in response to death signals, and executioner caspases, which are activated by the initiator caspases and are responsible for cleavage of cellular substrates that ultimately lead to cell death. Caspase-6 is an executioner caspase that was idientifed based on its homology with human caspases 2 and 3 as well as the C. elegans cell death protein CED-3. It possesses two isoforms, of which only the longer form possesses protease activity. Caspase-6 is highly expressed in adult brain and may play a role in several neuronal pathologies
Cite This Product ProSci cat# 3471 RRID:AB_713043
Company ProSci
Type Antibody
Accession Number NP_001217
Immunogen Caspase-6 antibody was raised against a 15 amino acid synthetic peptide from near the amino-terminus of human Caspase-6
Isotype IgG
Molecule Name CASP6 caspase 6, apoptosis-related cysteine peptidase
Clonality Polyclonal