Rabbit Anti-GCLC Polyclonal Antibody, Unconjugated

  • Rabbit Anti-GCLC Polyclonal Antibody, Unconjugated

    from ProSci
    CatalogueID : 48-485

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Target Gclc
Species Cross Reactivity Homo sapiens, Mus musculus, Monkey (Species unspecified)
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications WB, IHC, IP
Target/Molecule Synonym GCLC, EC 6.3.2.2, GAMMA-ECS, GCS, GLCL, GLCLC
Unit 0.05 mg
Format Purification: Protein A ColumnFormulation: Weight: 50 µg Volume: 250 µl Concentration: 0.2 mg/ml
Description Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. The gene for catalytic subunit (GLCLC) encodes a protein of 367 amino acids with a calculated molecular weight of 72.773 kDa and maps to chromosome 6. The regulatory subunit is derived from a different gene located on chromosome 1p21-p22. GLCLC deficiency in human is associated with enzymopathic hemolytic anemia.Immunogen: GCLC antibody was raised against amino acids 295 to 313 of GCLC. (Rat)Application: GCLC antibody can be used for detection of GCLC by WB (2 - 5 µg/ml), IP (10 µg/mg lysate), IHC-parafin (5 µg/ml).Buffer: GCLC antibody is supplied in PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide.Storage: GCLC antibody can be stored at 4ºC or -20ºC, Avoid repeated freezing and thawing.
Cite This Product ProSci cat# 48-485 RRID:AB_1946464
Company ProSci, Inc
Type Polyclonal Antibody