Mouse Anti-Human Apoa5 (ab) Monoclonal Antibody, Unconjugated, Clon...

  • Mouse Anti-Human Apoa5 (ab) Monoclonal Antibody, Unconjugated, Clone 1G5G9 (c)

    from ProSci
    CatalogueID : 32-109

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Target Apoa5
Species Cross Reactivity Homo sapiens
Host Species Mus musculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB
Clone Clone 1G5G9 (c)
Target Species Homo sapiens
Target/Molecule Synonym RAP3, APOAV, APOA-V
Unit 0.1 ml
Format Formulation: Purified antibody in PBS containing 0.03% sodium azide.
Description Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serum triglyceride concentrations. An ApoA5 mouse knock-out model produced an approximately four fold increase in serum triglycerides, whereas a knock-in model with human ApoA5 produced 50–70% lower concentrations of mouse serum triglycerides. In addition, peroxisome proliferator-activated receptor-_ agonists, which are used clinically to lower serum triglyceride concentrations, cause increased ApoA5 mRNA expression. Recently, it was demonstrated that ApoA5 is present in human serum detected by polyclonal antibodies against both the NH2 and COOH termini, although at much lower concentration than other apolipoproteins.GI Number: 116519Immunogen: Ni-NTA purified recombinant human APOA5 expressed in E. Coli strain BL21 (DE3).Application: Western Blot, ELISA. Dilution: Western Blot:1:2000 - 1:5,000 ELISA:Determining optimal working dilutions by titration test. Storage: Apoa5(ab) monoclonal antibody can be stored at -20ºC, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Cite This Product ProSci cat# 32-109 RRID:AB_1945124
Company ProSci, Inc
Type Monoclonal Antibody
Isotype IgG1
Uniprot ID Q8C7G5