Mouse Anti-Rapsyn Monoclonal Antibody, Unconjugated, Clone 1234

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Target RAPsyn
Species Cross Reactivity Amphibian (Species unspecified), Gallus gallus, Fish (Species unspecified), Mus musculus, Rattus norvegicus
Host Species Mus musculus
Target Tag/Conjugate Unconjugated
Applications IF, WB
Clone Clone 1234
Target Species Mus musculus
Target/Molecule Synonym 43 kDa receptor-associated protein of the synapse, RAPsyn, Acetylcholine receptor-associated 43 kDa protein, 43 kDa postsynaptic protein
Unit 100 ug
Format 100 ug of protein G purified antibody (1 mg/ml) in PBS containing 1 mg/ml BSA and 0.05% sodium azide.
NCBI Gene Aliases 43kDa, Raps, MGC130501, Nraps, rapsy, 43kDa,MGC130501,Nraps,Raps,rapsy
Description Jacobson C, Côté PD, Rossi SG, Rotundo RL, Carbonetto S. The dystroglycan complex is necessary for stabilization of acetylcholine receptor clusters at neuromuscular junctions and formation of the synaptic basement membrane. J Cell Biol. 2001 Feb 5;152(3):435-50.. PubMed PMID: 11157973Cartaud A, Coutant S, Petrucci TC, Cartaud J. Evidence for in situ and in vitro association between beta-dystroglycan and the subsynaptic 43K rapsyn protein. Consequence for acetylcholine receptor clustering at the synapse. J Biol Chem. 1998 May 1;273(18):11321-6.. PubMed PMID: 9556625Marchand S, Bignami F, Stetzkowski-Marden F, Cartaud J. The myristoylated protein rapsyn is cotargeted with the nicotinic acetylcholine receptor to the postsynaptic membrane via the exocytic pathway. J Neurosci. 2000 Jan 15;20(2):521-8.. PubMed PMID: 10632581Dai Z, Peng HB. A role of tyrosine phosphatase in acetylcholine receptor cluster dispersal and formation. J Cell Biol. 1998 Jun 29;141(7):1613-24.. PubMed PMID: 9647653Feng G, Steinbach JH, Sanes JR. Rapsyn clusters neuronal acetylcholine receptors but is inessential for formation of an interneuronal cholinergic synapse. J Neurosci. 1998 Jun 1;18(11):4166-76.. PubMed PMID: 9592096Meier T, Hauser DM, Chiquet M, Landmann L, Ruegg MA, Brenner HR. Neural agrin induces ectopic postsynaptic specializations in innervated muscle fibers. J Neurosci. 1997 Sep 1;17(17):6534-44.. PubMed PMID: 9254666
Company Thermo Scientific Pierce Antibodies
Clonality Monoclonal
Isotype IgG1
Immunogen Whole purified rapsyn from Torpedo californica electric organ postsynaptic membrane.
Gene Name receptor-associated protein of the synapse