Mouse Anti-CD49d Monoclonal Antibody, Unconjugated, Clone TA-2

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Target CD49D
Species Cross Reactivity Rattus norvegicus
Host Species Mus musculus
Target Tag/Conjugate Unconjugated
Applications FACS, IP
Clone Clone TA
Target Species Rattus norvegicus
Unit 250 ug
Format 250 µg of purified IgG in PBS.
Description . Inhibition of in vivo lymphocyte migration to inflammation and homing to lymphoid tissues by the TA-2 monoclonal antibody. A likely role for VLA-4 in vivo. J Immunol. 1991 Dec 15;147(12):4178-84.. PubMed PMID: 1753094Mastro AM, Schlosser DA, Grove DS, Lincoski C, Pishak SA, Gordon S, Kraemer WJ. Lymphocyte subpopulations in lymphoid organs of rats after acute resistance exercise. Med Sci Sports Exerc. 1999 Jan;31(1):74-81.. PubMed PMID: 9927013Brennan FM, Smith NM, Owen S, Li C, Amjadi P, Green P, Andersson A, Palfreeman AC, Hillyer P, Foey A, Beech JT, Feldmann M. Resting CD4+ effector memory T cells are precursors of bystander-activated effectors: a surrogate model of rheumatoid arthritis synovial T-cell function. Arthritis Res Ther. 2008;10(2):R36.. PubMed PMID: 18353171Larbi KY, Allen AR, Tam FW, Haskard DO, Lobb RR, Silva PM, Nourshargh S. VCAM-1 has a tissue-specific role in mediating interleukin-4-induced eosinophil accumulation in rat models: evidence for a dissociation between endothelial-cell VCAM-1 expression and a functional role in eosinophil migration. Blood. 2000 Nov 15;96(10):3601-9.. PubMed PMID: 11071660Davies D, Larbi K, Allen A, Sanz M, Weg VB, Haskard DO, Lobb RR, Nourshargh S. VCAM-1 contributes to rapid eosinophil accumulation induced by the chemoattractants PAF and LTB4: evidence for basal expression of functional VCAM-1 in rat skin. Immunology. 1999 May;97(1):150-8.. PubMed PMID: 10447726Machelska H, Brack A, Mousa SA, Schopohl JK, Rittner HL, Schäfer M, Stein C. Selectins and integrins but not platelet-endothelial cell adhesion molecule-1 regulate opioid inhibition of inflammatory pain. Br J Pharmacol. 2004 Jun;142(4):772-80.. PubMed PMID: 15159283
Company Thermo Scientific Pierce Antibodies
Type Monoclonal
Isotype IgG1
Immunogen Proprietary immunogen - Contact ABR for details.
Gene Name integrin, alpha 4