Rabbit Anti-TMEM173 Polyclonal Antibody

  • Rabbit Anti-TMEM173 Polyclonal Antibody

    CatalogueID : bs-8335R

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Target TMEM173
Species Cross Reactivity Canis lupus familiaris, Rattus norvegicus, Mus musculus, Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, IP, IHC, IF, IHC-Fr
Unit 100 ug Lyophilized
Format 1ug/uL, Two additional vials are included in shipment for reconstitution purposes (double distilled H20 and sterile glycerol). Centrifuge all vials to ensure necessary quantities have settled. Add 50uL of sterile double distilled water to antibody. Mix thoroughly by gently pipetting up and down. Then, add 50uL of sterile glycerol to antibody. Mix well and keep cold., *Please note lyophilized powder is supplied in bovine serum albumin and sodium azide. After reconstitution, final concentration of preservatives are 10ug/uL BSA and 0.1% NaN3
Concentration 1ug/uL
NCBI Gene Aliases Endoplasmic reticulum interferon stimulator;, ERIS;, FLJ38577;, hMITA;, hSTING;, Mediator of IRF3 activation;, MITA;, Mitochondrial mediator of IRF3 activation;, MPYS;, N terminal methionine proline tyrosine serine plasma membrane tetraspanner;, Stimulator of interferon genes;, Stimulator of interferon genes protein;, STING;, TM173_HUMAN;, Tmem173;, Transmembrane protein 173
Description Facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double-stranded DNA from viruses and bacteria delivered to the cytoplasm. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway
Company Bioss
Type Antibody
Immunogen KLH conjugated synthetic peptide derived from human TMEM173
Isotype IgG
Purity Was purified by Protein A and peptide affinity chromatography