Rabbit Anti-FAM134C Polyclonal Antibody

  • Rabbit Anti-FAM134C Polyclonal Antibody

    CatalogueID : bs-8153R

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Target Fam134c
Species Cross Reactivity Canis lupus familiaris, Rattus norvegicus, Mus musculus, Bos taurus, Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications EIA, WB, IP, IHC, IF, IHC-Fr
Unit 100 ug Lyophilized
Format 1ug/uL, Two additional vials are included in shipment for reconstitution purposes (double distilled H20 and sterile glycerol). Centrifuge all vials to ensure necessary quantities have settled. Add 50uL of sterile double distilled water to antibody. Mix thoroughly by gently pipetting up and down. Then, add 50uL of sterile glycerol to antibody. Mix well and keep cold., *Please note lyophilized powder is supplied in bovine serum albumin and sodium azide. After reconstitution, final concentration of preservatives are 10ug/uL BSA and 0.1% NaN3
Concentration 1ug/uL
NCBI Gene Aliases family with sequence similarity 134 member C;, FLJ33806;, hypothetical protein LOC162427;, Protein FAM134C;, DKFZp686B1036
Description Chromosome 17 makes up over 2.5% of the human genome with about 81 million bases encoding over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Tumor suppressor p53 is necessary for maintenance of cellular genetic integrity by moderating cell fate through DNA repair versus cell death. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes. Chromosome 17 is also linked to neurofibromatosis, a condition characterized by neural and epidermal lesions, and dysregulated Schwann cell growth. Alexander disease, Birt-Hogg-Dube syndrome and Canavan disease are also associated with chromosome 17. The FAM134C gene product has been provisionally designated FAM134C pending further characterization
Company Bioss
Type Antibody
Immunogen KLH conjugated synthetic peptide derived from human FAM134C
Isotype IgG
Molecular Weight 51kDa
Purity Was purified by Protein A and peptide affinity chromatography