Rabbit Anti-ZNRF1 Polyclonal Antibody

  • Rabbit Anti-ZNRF1 Polyclonal Antibody

    CatalogueID : bs-9139R

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Target znrf1
Species Cross Reactivity Rattus norvegicus, Homo sapiens, Mus musculus
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications IF, IHC-Fr, EIA, IHC, FC, IP
Unit 100 ug Lyophilized
Format 1ug/uL, Two additional vials are included in shipment for reconstitution purposes (double distilled H20 and sterile glycerol). Centrifuge all vials to ensure necessary quantities have settled. Add 50uL of sterile double distilled water to antibody. Mix thoroughly by gently pipetting up and down. Then, add 50uL of sterile glycerol to antibody. Mix well and keep cold., *Please note lyophilized powder is supplied in bovine serum albumin and sodium azide. After reconstitution, final concentration of preservatives are 10ug/uL BSA and 0.1% NaN3
Concentration 1ug/uL
NCBI Gene Aliases E3 ubiquitin protein ligase ZNRF1;, E3 ubiquitin-protein ligase ZNRF1;, Nerve injury gene 283;, Nerve injury induced gene 283 protein;, Nerve injury-induced gene 283 protein;, NIN283;, Rnf42;, Zinc and ring finger 1;, zinc and ring finger protein 1;, zinc finger and ring finger protein 1;, Zinc/RING finger protein 1;, ZNRF 1;, znrf1;, ZNRF1_HUMAN;, Zrfp1
Description Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. ZNRF1 (zinc and ring finger 1), also known as NIN283, is a 227 amino acid protein that contains one RING-type zinc finger and localizes to the lysosome and the endosome, as well as to cytoplasmic vesicles and the peripheral membrane. Expressed primarily in nervous system tissue, but also present in testis and thymus, ZNRF1 functions as an E3 ubiquitin-protein ligase that is thought to play a role in the establishment and maintenance of neuronal plasticity. Multiple isoforms of ZNRF1 exist due to alternative splicing events
Company Bioss
Type Antibody
Immunogen KLH conjugated synthetic peptide derived from human ZNRF1
Isotype IgG
Purity Was purified by Protein A and peptide affinity chromatography