Rabbit Anti-LMP7 Polyclonal Antibody

  • Rabbit Anti-LMP7 Polyclonal Antibody

    CatalogueID : bs-9364R

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Target Lmp7
Species Cross Reactivity Mus musculus, Rattus norvegicus, Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications IHC-Fr, EIA, IHC, IF, WB
Unit 100 ug Lyophilized
Format 1ug/uL, Two additional vials are included in shipment for reconstitution purposes (double distilled H20 and sterile glycerol). Centrifuge all vials to ensure necessary quantities have settled. Add 50uL of sterile double distilled water to antibody. Mix thoroughly by gently pipetting up and down. Then, add 50uL of sterile glycerol to antibody. Mix well and keep cold., *Please note lyophilized powder is supplied in bovine serum albumin and sodium azide. After reconstitution, final concentration of preservatives are 10ug/uL BSA and 0.1% NaN3
Concentration 1ug/uL
NCBI Gene Aliases Proteasome 20S LMP7;, D6S216;, D6S216E;, Large multifunctional peptidase 7;, Large multifunctional protease 7;, LMP 7;, LMP-7;, LMP7;, Low molecular mass protein 7;, Low molecular weight protein 7;, Macropain subunit C13;, MGC1491;, Multicatalytic endopeptidase complex subunit C13;, Protease component C13;, Proteasome (prosome macropain) subunit beta type 8;, Proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7);, Proteasome beta 8 subunit;, Proteasome catalytic subunit 3i;, Proteasome component C13;, Proteasome related gene 7;, Proteasome subunit beta 5i;, Proteasome subunit beta type 8;, Proteasome subunit beta type;, Proteasome subunit beta type-8;, Proteasome subunit beta-5i;, Proteasome subunit Y2;, PSB8_HUMAN;, PSMB 8;, PSMB5i;, PSMB8;, Really interesting new gene 10 protein;, RING 10;, RING10;, Y2 antibody
Description The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. Replacement of PSMB5 by PSMB8 increases the capacity of the immunoproteasome to cleave model peptides after hydrophobic and basic residues. Acts as a major component of interferon gamma-induced sensitivity. Plays a key role in apoptosis via the degradation of the apoptotic inhibitor MCL1. May be involved in the inflammatory response pathway. In cancer cells, substitution of isoform 1 (E2) by isoform 2 (E1) results in immunoproteasome deficiency
Company Bioss
Type Antibody
Immunogen KLH conjugated synthetic peptide derived from human LMP7
Isotype IgG
Molecular Weight 20kDa
Purity Was purified by Protein A and peptide affinity chromatography