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| Target | Xrcc6 |
| Species Cross Reactivity | Oryctolagus cuniculus, Mus musculus, Primate (Species unspecified), Bos taurus, Homo sapiens |
| Host Species | Mus musculus |
| Target Tag/Conjugate | Unconjugated |
| Applications | WB, IP, IF |
| Clone | S5C11 |
| Target Species | Homo sapiens |
| Target/Molecule Synonym | XRCC6, 5-dRP lyase Ku70, 70 kDa subunit of Ku antigen, CTCBF, DNA repair protein XRCC6, D22S671, D22S731, G22P1, Ku autoantigen, 70kDa, Ku autoantigen p70 subunit, Thyroid-lupus autoantigen p70, TLAA, CTC75, KU70, ML8, Thyroid-lupus autoantigen |
| Unit | 0.5 ml |
| Format | 0.05% sodium azide |
| NCBI Gene Aliases | CTC75, KU70, TLAA, CTCBF, ML8, G22P1 |
| Description | Specificity: Reacts with a 70 kD protein known as Ku (p70). Ku autoantigen is a heterodimer of p70 kD (p70) and 80 kD (p80) proteins. The p70/p80 dimer is important for the function of a 460 kD DNA-dependant protein kinas that phosphorylates certain transcription factors, including sp1, Oct-1, p53 and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation and apoptosis. This antibody cross reacts with monkey but does not cross react with cow, rabbit and mouse. |
| Cite This Product | LifeSpan BioSciences cat# LS-C95524-0.5 RRID:AB_10561662 |