H2AX Rabbit anti-Human Polyclonal (C-Terminus) Antibody

  • H2AX Rabbit anti-Human Polyclonal (C-Terminus) Antibody

    CatalogueID : LS-B3282-50

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Target h2afx
Species Cross Reactivity Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications WB, IHC, IF
Target Species Homo sapiens
Target/Molecule Synonym H2AFX, H2AX, Histone H2A.x, H2A.X, H2A histone family, member X, H2AX histone
Unit 50 Ķg
Format Tris-citrate/phosphate, 0.09% sodium azide
Concentration 1 mg/ml
NCBI Gene Aliases H2AX, H2A/X, H2A.X
Description Specificity: Specific for human histone H2AX. H2AX comprises approximately 2-25% of the histone H2A pool in mammalian cells. The extended C-terminal tail of H2AX contains a serine (Ser139) embedded in an conserved SQE motif, which is rapidly phosphorylated at sites of double strand breaks and stalled replication forks. Phosphorylated H2AX may serve to recruit other repair proteins to the site of DNA damage. H2AX has been implicated in both homologous recombination and nonhomologous end joining DNA repair pathways
Cite This Product LifeSpan BioSciences cat# LS-B3282-50 RRID:AB_10567804
Company LifeSpan BioSciences
Type Antibody
Domain/Region/Terminus C-Terminus
Isotype IgG
Purity Immunoaffinity purified
Uniprot ID P16104
Clonality Polyclonal