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| Target | CD3 |
| Species Cross Reactivity | Mus musculus, Homo sapiens |
| Host Species | Mus musculus |
| Target Tag/Conjugate | RPE |
| Applications | FC |
| Clone | APA1/1 |
| Unit | 100 µg |
| Format | 15 mM sodium azide, 0.2% BSA, PBS |
| Description | Specificity: The mouse monoclonal antibody APA1/1 recognizes an activation-dependent intracellular epitope of CD3 epsilon. Exposure of the epitope precedes CD3 phosphorylation and recruitment and activation of ZAP70, which initiates the signaling cascade produced by T-cell activation. APA1/1 provides the earliest known marker for TCR-mediated T cell activation. |
| Cite This Product | LifeSpan BioSciences cat# LS-C112557-100 RRID:AB_10698905 |
| Company | LifeSpan BioSciences |
| Type | Antibody |
| Isotype | IgG1 |