XRCC6 / Ku70 Mouse anti-Human Monoclonal (S5C11) Antibody

  • XRCC6 / Ku70 Mouse anti-Human Monoclonal (S5C11) Antibody

    CatalogueID : LS-C95524-1

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Target Xrcc6
Species Cross Reactivity Oryctolagus cuniculus, Mus musculus, Primate (Species unspecified), Bos taurus, Homo sapiens
Host Species Mus musculus
Target Tag/Conjugate Unconjugated
Applications WB, IP, IF
Clone S5C11
Target Species Homo sapiens
Target/Molecule Synonym XRCC6, 5-dRP lyase Ku70, 70 kDa subunit of Ku antigen, CTCBF, DNA repair protein XRCC6, D22S671, D22S731, G22P1, Ku autoantigen, 70kDa, Ku autoantigen p70 subunit, Thyroid-lupus autoantigen p70, TLAA, CTC75, KU70, ML8, Thyroid-lupus autoantigen
Unit 1 ml
Format 0.05% sodium azide
NCBI Gene Aliases CTC75, KU70, TLAA, CTCBF, ML8, G22P1
Description Specificity: Reacts with a 70 kD protein known as Ku (p70). Ku autoantigen is a heterodimer of p70 kD (p70) and 80 kD (p80) proteins. The p70/p80 dimer is important for the function of a 460 kD DNA-dependant protein kinas that phosphorylates certain transcription factors, including sp1, Oct-1, p53 and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation and apoptosis. This antibody cross reacts with monkey but does not cross react with cow, rabbit and mouse.
Cite This Product LifeSpan BioSciences cat# LS-C95524-1 RRID:AB_10561663
Company LifeSpan BioSciences
Type Antibody
Isotype IgG1 kappa
Purity Ig fraction
Uniprot ID P12956
Clonality Monoclonal