GZMB / Granzyme B Mouse anti-Human Monoclonal (GRB-7) Antibody

  • GZMB / Granzyme B Mouse anti-Human Monoclonal (GRB-7) Antibody

    CatalogueID : LS-C121911-1000

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Target Gzmb
Species Cross Reactivity Homo sapiens
Host Species Mus musculus
Target Tag/Conjugate Unconjugated
Applications WB, IHC, IHC-Fr
Clone GRB-7
Target Species Homo sapiens
Target/Molecule Synonym GZMB, CCPI, CGL-1, Cathepsin G-like 1, CSP-B, CTLA-1, CTLA1, CGL1, CSPB, Fragmentin 2, GRB, HLP, Human lymphocyte protein, Fragmentin-2, SECT, Lymphocyte protease, T-cell serine protease 1-3E, C11, CTSGL1, Cytotoxic serine protease B, Granzyme B, Granzyme-2
Unit 1000 Ķl
Format 1% BSA, 0.1% sodium azide
NCBI Gene Aliases CSP-B, CTLA1, CGL1, CGL-1, CCPI, HLP, CTSGL1, SECT, CSPB
Description Specificity: Recognizes the 33kD human serine protease granzyme B. Does not react with human granzyme A. It is used as a marker for NK-cells and activated cytotoxic T-cells (CTL). This protease is localized in cytoplasmic granules and gives a granular staining pattern. Granzyme B is involved in target cell apoptosis during lymphocyte mediated cyto-toxicity. Exocytosis of granzyme containing granules in the cytoplasm of the target cell will lead to induction of DNA fragmentation and apoptosis of the target cell.
Cite This Product LifeSpan BioSciences cat# LS-C121911-1000 RRID:AB_10799879
Company LifeSpan BioSciences
Type Antibody
Isotype IgG2a
Purity Tissue culture supernatant
Uniprot ID P10144
Clonality Monoclonal