FIV gp95 Mouse anti-Cat Monoclonal (SU1-30) Antibody

  • FIV gp95 Mouse anti-Cat Monoclonal (SU1-30) Antibody

    CatalogueID : LS-C58139-250

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Target Gp95
Species Cross Reactivity Felis catus
Host Species Mus musculus
Target Tag/Conjugate Unconjugated
Applications WB, FC, Functional Assay
Clone SU1-30
Unit 250 Ķg
Format PBS, pH 7.2, 0.05% sodium azide
Description Specificity: Recognizes the relatively conserved E60 peptide (amino acid sequence SSWKQRNRWEWRPDF) located within the V3 region of FIV (Feline Immunodeficiency Virus) envelope glycoprotein SU,gp95. The primary receptor for FIV infection of cats has been identified as the T-cell activation antigen CD134 which, along with CXC chemokine receptor 4 (CXCR4), facilitates the infection of CD4+ primary target cells, resulting in a depletion in the CD4+ population. Studies have shown that the V3 loop of SU,gp95 is a ma a major immunogenic domain, suggested to contain the main determinants for the binding of FIV SU,gp95 to CXCR4. Clone SU1-30 has been shown to inhibit the sCD134-activated entry of both clade B and clade C FIV strains. Does not recognize Feline Leukaemia Virus, Feline Herpes Virus type 1, Feline Coronavirus or Feline Calicivirus. Removal of Sodium Azide is recommended prior to use in functional studies
Cite This Product LifeSpan BioSciences cat# LS-C58139-250 RRID:AB_10560611
Company LifeSpan BioSciences
Type Antibody
Isotype IgG1
Purity Affinity purified
Clonality Monoclonal