TIMP2 / TIMP-2 Mouse anti-Human Monoclonal (N-Terminus) (3A4) Antibody

  • TIMP2 / TIMP-2 Mouse anti-Human Monoclonal (N-Terminus) (3A4) Antibody

    CatalogueID : LS-C95516-1

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Target TIMP2
Species Cross Reactivity Sus scrofa, Oryctolagus cuniculus, Rattus norvegicus, Mus musculus, Bos taurus, Cavia porcellus, Homo sapiens
Host Species Mus musculus
Target Tag/Conjugate Unconjugated
Applications WB
Clone 3A4
Target Species Homo sapiens
Target/Molecule Synonym TIMP2, Metalloproteinase inhibitor 2, TIMP-2, CSC-21K
Unit 1 ml
Format 0.05% sodium azide
NCBI Gene Aliases CSC-21K, DDC8
Description Specificity: Is specific to 21 kD protein known as TIMP-2. TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family. TIMPs are of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72 kD Type IV collagenase (MMP-2) and active form of 92 kD Type IV collagenase (MMP-9). TIMPs inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. This antibody cross reacts with mouse, rat, rabbit, cow and Guinea pig.
Cite This Product LifeSpan BioSciences cat# LS-C95516-1 RRID:AB_10561248
Company LifeSpan BioSciences
Type Antibody
Domain/Region/Terminus N-Terminus
Isotype IgG2a kappa
Purity Ig fraction
Uniprot ID P16035
Clonality Monoclonal