Complement C6 / C6 Mouse anti-Human Monoclonal (C-Terminus) (056B-2...

  • Complement C6 / C6 Mouse anti-Human Monoclonal (C-Terminus) (056B-214.2.4.2) Antibody

    CatalogueID : LS-B3294-50

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Target C6
Species Cross Reactivity Homo sapiens
Host Species Mus musculus
Target Tag/Conjugate Unconjugated
Applications EIA, FC, IHC
Clone 056B-214.2.4.2
Target Species Homo sapiens
Target/Molecule Synonym C6, Complement component C6, Complement C6, Complement component 6
Unit 50 Ķg
Format Borate buffered saline, 0.09% sodium azide. Sourced in Ascites
Concentration 1 mg/ml
Description Specificity: Recognizes complement component 6 (C6) a 104 kD member of the complement C6/C7/C8/C9 family present in blood serum. The factor I modules of C6 bind the C terminus of the C5b alpha-chain, anchoring the molecule to the membrane and also binds complement component 7. This enables the formation of the C5b-7 precursor complex. C5b-7 then functions as a receptor for components C8 and C9 which form the complement membrane attack complex (MAC). Deficiency of C6 results in susceptibility to bacterial infection. Recognizes MAC.
Cite This Product LifeSpan BioSciences cat# LS-B3294-50 RRID:AB_10573634
Company LifeSpan BioSciences
Type Antibody
Domain/Region/Terminus C-Terminus
Isotype IgG1
Purity Protein A purified
Uniprot ID P13671
Clonality Monoclonal