KLHL13 antibody (FITC)

  • KLHL13 antibody (FITC)

    from biorbyt
    CatalogueID : orb102870

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Target KLHL13
Species Cross Reactivity Rattus norvegicus, Mus musculus, Danio rerio, Homo sapiens, Bos taurus
Host Species Oryctolagus cuniculus
Target Tag/Conjugate FITC
Applications ICC, IF
Target/Molecule Synonym Anti-KLHL13 (kelch like 13), also known as BKLHD2 (BTB and kelch domain containing protein 2), is a 604 amino acid protein that contains six Kelch repeats and one BTB/POZ domain. Expressed predominantly in brain, KLHL13 is believed to play a role in protein ubiquitination and may function as a substrate specific adapter of an E3 ubiquitin protein ligase complex. E3 ligases accept a ubiquitin residue from an E2 ubiquitin conjugating enzyme and immediately transfer that residue to a protein that is targeted for degradation. Specifically, KLHL13 interacts with KLHL9 and CUL3, a member of the cullin family of mediators that participate in the selective targeting of proteins for ubiquitin mediated proteolysis. Via its BTB and C terminal Kelch (BACK) motif, KLHL13 is thought to play a role in spatially orientating substrates in the CUL3 ligase. antibody
Unit 100 ug
Format Liquid: 10 mM PBS, pH 7.4 with 10 mg/ml BSA and 0.1% sodium azide
Description Rabbit Polyclonal to KLHL13 conjugated to FITC
Company Biorbyt
Type Antibody
Isotype IgG
Molecular Weight 74 kDa
Purity Affinity purified
Clonality Polyclonal