Ku80 antibody

  • Ku80 antibody

    from biorbyt
    CatalogueID : orb41581

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Target Ku80
Species Cross Reactivity Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications IHC, WB, IF, ICC
Target/Molecule Synonym anti-XRCC5 antibody
Unit 100 ul
Format 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7)
Description Rabbit polyclonal to Ku80. The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [provided by RefSeq]
Company Biorbyt
Type Antibody
Immunogen Recombinant protein fragment contain a sequence corresponding to a region within amino acids 315 and 563 of Ku80 (XRCC5)
Purity Purified by antigen-affinity chromatography
Clonality Polyclonal