Lamin A Antibody

  • Lamin A Antibody

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    CatalogueID : orb41699

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Target Lamin A
Species Cross Reactivity Homo sapiens
Host Species Oryctolagus cuniculus
Target Tag/Conjugate Unconjugated
Applications IHC-P, WB
Target Species Homo sapiens
Unit 100 μg
Concentration 1 mg/ml
Description Rabbit polyclonal to Lamin A. The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Through alternate splicing, this gene encodes three type A lamin isoforms. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq]
Cite This Product Biorbyt cat# orb41699 RRID:AB_10991863
Immunogen Lamin A
Product Name Alias anti-Lamin C antibody
Clonality Polyclonal