Men 10376

  • Contact Vendor

Target Tag/Conjugate Unconjugated
Format Purity: > 95%
Category Peptide
Original Item Name Men 10376
Molecule Name Men 10376
Unit 1 mg
Description Men 10376 is a potent and selective NK2 tachykinin receptor antagonist. MEN 10.376 was devoid of significant agonist activity at i.v. doses (1-3 mumol/kg) which selectively antagonized the effects of an NK-2 agonist [beta-Ala8]-neurokinin A(4-10) (bladder contraction in rats. bronchoconstriction in guinea pigs) without affecting the response to an NK-1 agonist [Sar9]-substance P sulfone (hypotension. salivation and bladder contraction in rats. bronchoconstriction in guinea pigs). MW: 108122 Testing Protocols: Structure: ||06-271-83335_STRUCTURE Cross-Reactivity: Storage: 4°C for short term (weeks) and -20°C for long term. Stability: 6-12 months at -20°C. Sequence (One Letter Code): DYWVWWK-NHSequence: {ASP} {TYR} {d-TRP} {VAL} {d-TRP} {d-TRP} {LYS}-NH2 Product ID: 83335