Human KIR3DL1, Cytoplasmic tail, aa 361-444 , His Conjugated/Tagged

  • Human KIR3DL1, Cytoplasmic tail, aa 361-444 , His Conjugated/Tagged

    CatalogueID : GWB-9CEB0C

  • Contact Vendor

Target Tag/Conjugate His
Target/Molecule Synonym KIR3DL1, Q1PSF1_HUMAN
Species Human
Format Purity: >= 95% by SDS PAGE
Format: Liquid. In 25mM Tris-HCl (pH7.5) 100mM NaCl.
Source/Expression System E. Coli
Applications SDS
Category Protein
References [1] Norman.P.J. and Parham.P. et al.
KIR3DL1 polymorphism
[2] Norman.P.J. and Parham.P. et al.
Direct Submission
[3] Norman P.J. Parham P.
KIR3DL1 polymorphism.
Original Item Name KIR3DL1 (Cytoplasmic tail. 361-444aa. His-tag. human)
Molecule Name KIR3DL1, Cytoplasmic tail, aa 361-444
Unit 0.1 mg
Description The three Ig-domain from of inhibitory killer cell Ig-like receptor 1 (KIR3DL1.NKB1. nkat3. p70KIR) is a NK cell receptor for polymorphic HLA-B determinant. KIR3DLl recognizes the Bw4 determinant defined by sequence motifs at positins 77-83 of the HLA-B heavy chain. The cytoplasmic tail of KIR. which contains two immunoreceptor tyrosine-based inhibition motifs (ITIMs). mediates inhibitory signal transduction that prevents killer cell-mediated cytotoxicity. A His-tag fusion protein of KIR3DL1 cytoplasmic tail (361-444aa) was overexpressed as insoluble protein aggregates(inclusion bodies). This protein was purified by FPLC gel-filtration chromatography. after refolding of the isolated inclusion bodies in a redox buffer.N/A Sequence Position 1: 361 Sequence Position 2: 444 Sequence Length (aa): 444 MW: 48954 Applications Tested: SDS Applications Not Tested: MS Testing Protocols: SDS: 14% SDS PAGE||10-002-38038_SDHuman Storage: Store at -20°C. Avoid frequent freeze and thaw. Stability: 6-12 months at -70°C. Product ID: 38038