Human Angiotensin II

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Target Tag/Conjugate Unconjugated
Target/Molecule Synonym Angiotensin II, Type-1 angiotensin II receptor, AT1, AT1AR, AT1BR, AGTR1A, AGTR1B, AT2R1, AT2R1B
Format Purity: > 95%
Species Human
Molecule Name Angiotensin II
References [1] Takei.Y.. Hasegawa.Y.. Watanabe.T.X.. Nakajima.K. and Hazon.N.. et al.
A novel angiotensin I isolated from an elasmobranch fish
Category Peptide
Original Item Name Angiotensin II Human
Accession Number NCBI Accession Number: CAA77513.1
Swiss Protein Accession Number: P30556
Unit 5 mg
Description Angiotensin II (ANG II) is an important physiological effector of blood pressure and volume regulation through vasoconstriction. aldosterone release. sodium uptake and thirst stimulation. Angiotensin II mediates its action by interacting with membrane receptor. Angiotensin II type 1 receptors.Function: Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.Subcellular Location: Membrane; multi-pass membrane protein.Tissue Specificity: Liver. lung. adrenal and adrenocortical adenomas.Ptm: C-terminal Ser or Thr residues may be phosphorylated.Similarity: Belongs to the G-protein coupled receptor 1 family [view classification]. Entry Name: AGTR1_HUMAN Length (aa): 359 MW: 41061 OMIM: 106165; gene. [ NCBI / EBI] Testing Protocols: Structure: ||06-271-83073_STRUCTURE Storage: 4°C for short term (weeks) and -20°C for long term. Stability: 6-12 months at -20°C. Sequence (One Letter Code): DRVYIHPFSequence: {ASP} {ARG} {VAL} {TYR} {ILE} {HIS} {PRO} {PHE} Formula: C50H71N13O12 Solubility: Soluble in water (25 mg/mL). clear. colorless.