Lipid-transfer protein CERTL

  • Lipid-transfer protein CERTL

    CatalogueID : GWB-BD77E0

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Target/Molecule Synonym CERT, CERT, GPBP, CERTL, STARD11, Q53YV1_HUMAN
Target Tag/Conjugate Unconjugated
Format Purity: 0.95
Format: 10 mM Tris. pH 8.0. 0.002% NaN3. 3mM NaCl. 2.5mM Imidazole.
Applications MS, SDS
References [1] Longo.I. Scala.E. Mari.F. Caselli.R. Pescucci.C. Mencarelli.M.A. Speciale.C. Giani.M. Bresin.E. Caringella.D.A. et al.
Autosomal recessive Alport syndrome: an in-depth clinical and molecular analysis of five families
[2] Granero.F. Revert.F. Revert-Ros.F. Lainez.S. Martinez-Martinez.P. and Saus.J.
A human-specific TNF-responsive promoter for Goodpasture antigen-binding protein
[3] Borza.D.B. Bondar.O. Colon.S. Todd.P. Sado.Y. Neilson.E.G. and Hudson.B.G.
Goodpasture autoantibodies unmask cryptic epitopes by selectively dissociating autoantigen complexes lacking structural reinforcement: novel mechanisms for immune privilege and autoimmune pathogenesis
[4] Kumagai.K. Yasuda.S. Okemoto.K. Nishijima.M. Kobayashi.S. and Hanada.K.
CERT mediates intermembrane transfer of various molecular species of ceramides
[5] Hanada.K. Kumagai.K. Yasuda.S. Miura.Y. Kawano.M. Fukasawa.M. and Nishijima.M.
Molecular machinery for non-vesicular trafficking of ceramide
[6] . Hanada K. Kumagai K. Yasuda S. Miura Y. Kawano M. Fukasawa M. Nishijima M.
Molecular machinery for non-vesicular trafficking of ceramide.
Category Protein
Original Item Name Lipid-transfer protein CERTL
Source/Expression System E. coli
Molecule Name Lipid-transfer protein CERTL
Unit 0.05 mg
Description Similarity: Contains 1 PH domain.Summary: This protein is a kinase that specifically phosphorylates the N-terminal region of the non-collagenous domain of the alpha 3 chain of type IV collagen. known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Two transcripts exist for this gene. Chromosome Location: 5q13.3 Sequence Position 1: 1 Sequence Position 2: 598 Sequence Length (aa): 598 MW: 70835 OMIM: NCBI [ 604677] Applications Tested: MS. SDS Applications Not Tested: ELISA. Western Blot Testing Protocols: SDS: Analysis of COL4A3BP Recombinant Protein. 4-20% SDS gradient gel. Coomassie blue staining.||10-288-22128F_SDhuman Storage: -70°C. Avoid frequent freeze and thaw. Stability: 6-12 months at -70°C. Fusion: His-Tag at N-terminus. Product ID: 5108