Dermaseptin

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Target Tag/Conjugate Unconjugated
Target/Molecule Synonym Dermaseptin [Phyllomedusa bicolor], Dermaseptin DRG1, Dermaseptin-1
Format Purity: > 95%
Category Peptide
Original Item Name Dermaseptin
Accession Number NCBI Accession Number: CAC37582.1
Swiss Protein Accession Number: Q90ZK3
Molecule Name Dermaseptin
Unit 1 mg
Description Dermaseptins are antimicrobial peptides. strings of amino acids. or proteins. of various sizes and shapes. Dermaseptins were isolated from frog skin. Dermaseptin is a crucial part of the frog's immune system. inhibiting the growth of bacteria. protozoa and fungi. Dermaseptins are cationic (positively charged) and 27-34 residues in length. Dermaseptins adopt a largely K-helical conformation when binding to membranes. Like other antimicrobial peptides. dermaseptin is membrane-perturbing; however. unlike other antimicrobial peptides. dermaseptin rests on the surface of the bacterial membrane and does not insert.Function: Has antimicrobial activity (Potential).Subcellular Location: Secreted protein (Probable).Tissue Specificity: Expressed by the skin glands.Similarity: Belongs to the frog skin active peptide (FSAP) family. Dermaseptin subfamily. Entry Name: DRG1_PHYBI Length (aa): 81 MW: 8756 Storage: 4°C for short term (weeks) and -20°C for long term. Stability: 6-12 months at -20°C. Sequence (One Letter Code): ALWKTMLKKLGTMALHAGKAALGAAADTISQGTQSequence: {ALA} {LEU} {TRP} {LYS} {THR} {MET} {LEU} {LYS} Formula: C152H257N43O44S2