Human Neuropeptide Y, aa 13-36

  • Human Neuropeptide Y, aa 13-36

    CatalogueID : 06-271-83354

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Species Human
Format Purity: > 95%
Target/Molecule Synonym NPY, NPY_HUMAN
Target Tag/Conjugate Unconjugated
References [1] Coiro.V. Chiodera.P. Melani.A. Manfredi.G. Saccani Jotti.G. and Casti.A.
Different plasma neuropeptide Y concentrations in women athletes with and without menstrual cyclicity
[2] Colton.C.A. and Vitek.M.P. et al.
NPY and chronic neurodegenerative disease
[3] Dutton.M.A. Lee.E.W. and Zukowska.Z. et al.
NPY and extreme stress: lessons learned from posttraumatic stress disorder
[4] Feuerstein.G.Z. and Lee.E.W. et al.
Neuropeptide Y and the heart: implication for myocardial infarction and heart failure
[5] Edvinsson.L. et al.
Neuropeptide Y and the cerebral circulation
[6] Minth C.D. Bloom S.R. Polak J.M. Dixon J.E.
Cloning. characterization. and DNA sequence of a human cDNA encoding neuropeptide tyrosine.
[7] Minth C.D. Andrews P.C. Dixon J.E.
Characterization. sequence. and expression of the cloned human neuropeptide Y gene.
[8] Takeuchi T. Gumucio D.L. Yamada T. Meisler M.H. Minth C.D. Dixon J.E. Eddy R.E. Shows T.B.
Genes encoding pancreatic polypeptide and neuropeptide Y are on human chromosomes 17 and 7.
[9] Hillier L.W. Fulton R.S. Fulton L.A. Graves T.A. Pepin K.H. Wagner-McPherson C. Layman D. Maas J. Jaeger S. Walker R. et al.
The DNA sequence of human chromosome 7.
[10] Allen J.M. Polak J.M. Bloom S.R.
Presence of the predicted C-flanking peptide of neuropeptide Y (CPON) in tissue extracts.
Molecule Name Neuropeptide Y, aa 13-36
Original Item Name Neuropeptide Y (13-36) Human
Category Peptide
Unit 5 mg
Description The C-terminal NPY fragment (13-36)[NPY-(13-36)]. a Y2 receptor agonist. elicits vasopressor responses upon central administration. The cardiovascular responses of NPY-(13-36) together with the distribution of NPY receptor subtypes within the nucleus tractus solitarius (nTS) have therefore been studied in spontaneously hypertensive rats (SHR).Neuropeptide Y (13-36)(NPY 13-36) stimulates both Y2 and Y5 NPY receptor subtypes. but causes no increase in food intake even when injected at high doses. while the full length NPY is one of the most potent physiological stimulants of feeding yet described. It inhibits retinotectal transfer in amphibians.Function: NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone.Subcellular Location: Secreted protein.Tissue Specificity: One of the most abundant peptides in the nervous system. Also found in some chromaffin cells of the adrenal medulla.Similarity: Belongs to the NPY family. Sequence Position 1: 13 Sequence Position 2: 36 Sequence Length (aa): 97 MW: 10851KEGG pathway: Adipocytokine signaling pathway 04920KEGG pathway: Neuroactive ligand-receptor interaction 04080 OMIM: 162640; gene. [ NCBI / EBI]Human Storage: 4°C for short term (weeks) and -20°C for long term. Stability: 6-12 months at -20°C. Sequence (One Letter Code): PAEDMARYYSALRHYINLITRQRYNHSequence: {PRO} {ALA} {GLU} {ASP} {MET} {ALA} {ARG} {TYR} {TYR} {SER} {ALA} {LEU} {ARG} {HIS} {TYR} {ILE} {ASN} {LEU} {ILE} {THR} {ARG} {GLN} {ARG} {TYR}NH2 Product ID: 83354