Ras-related protein Rab-4A , N-Terminus T7 Conjugated/Tagged

  • Ras-related protein Rab-4A , N-Terminus T7 Conjugated/Tagged

    CatalogueID : GWB-A62780

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Format Purity: 0.95
Format: 10 mM Tris. pH 8.0. 0.1% Triton X-100. 0.002% NaN3.
Target/Molecule Synonym RAB4A. member RAS oncogene family, Oncogene RAB4, RAB4. member RAS oncogene family, RAB4A, RAB4
Target Tag/Conjugate N-Terminus T7
Accession Number Accession Number: NP_004569.1
Sp Accession Number: P20338
Category Protein
Molecule Name Ras-related protein Rab-4A
References [1] Rousseau-Merck. M. F. Zahraoui. A. Touchot. N. Tavitian. A. and Berger. R.
Chromosome assignment of four RAS-related RAB genes
[2] Zahraoui. A. Touchot. N. Chardin. P. and Tavitian. A. et al.
The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion
[3] . Zahraoui A. Touchot N. Chardin P. Tavitian A.
The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion.
[4] . Puhl H. L. III. Ikeda S. R. Aronstam R. S.
cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www. cdna. org).
[5] . Strausberg R. L. Feingold E. A. Grouse L. H. Derge J. G. Klausner R. D. Collins F. S. Wagner L. Shenmen C. M. Schuler G. D. Altschul S. F. et al.
Generation and initial analysis of more than 15. 000 full-length human and mouse cDNA sequences.
[6] . Bailly E. McCaffrey M. Touchot N. Zahraoui A. Goud B. Bornens M.
Phosphorylation of two small GTP-binding proteins of the Rab family by p34cdc2.
[7] . van der Sluijs P. Hull M. Huber L. A. Male P. Goud B. Mellman I.
Reversible phosphorylation-dephosphorylation determines the localization of rab4 during the cell cycle.
[8] . Nagelkerken B. van Anken E. van Raak M. Gerez L. Mohrmann K. van Uden N. Holthuizen J. Pelkmans L. van der Sluijs P.
Rabaptin4. a novel effector of the samll GTPase rab4a. is recruited to perinuclear recycling vesicles.
[9] . Lindsay A. J. Hendrick A. G. Cantalupo G. Senic-Matuglia F. Goud B. Bucci C. McCaffrey M. W.
Rab coupling protein (RCP). a novel Rab4 and Rab11 effector protein.
[10] . de Renzis S. Soennichsen B. Zerial M.
Divalent Rab effectors regulate the sub-compartmental organization and sorting of early endosomes.
Applications MS, SDS
Original Item Name Ras-related protein Rab-4A
Source/Expression System E. coli
Unit 0.05 mg
Description Function: Protein transport. Probably involved in vesicular traffic (By similarity).Subunit: Interacts with RAB11FIP1. RABEP1. ZFYVE20 and RUFY1.Subcellular Location: Membrane; peripheral membrane protein. Generally associated with membranes. Cytoplasm. Cytoplasmic when phosphorylated by CDC2.Ptm: Phosphorylated by CDC2 kinase during mitosis.Similarity: Belongs to the small GTPase superfamily. Rab family. Chromosome Location: 1q42-q43 Sequence Position 1: 1 Sequence Position 2: 213 Sequence Length (aa): 213 MW: 23871 OMIM: 179511; gene. [ NCBI / EBI] Applications Tested: MS. SDS Applications Not Tested: ELISA. Western Blot Testing Protocols: SDS: Analysis of RAB4A Recombinant Protein. 4-20% SDS gradient gel. Coomassie blue staining.||10-288-22077F_SD Cross-Reactivity: human Storage: -70°C. Avoid frequent freeze and thaw. Stability: 6-12 months at -70°C. Fusion: T7 tag at N-terminus. Fusion: T7 tag at N-terminus. Product ID: 5083