Calcineurin Autoinhibitory Peptide

  • Calcineurin Autoinhibitory Peptide

    CatalogueID : GWB-1D0E30

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Format Purity: > 95%
Target Tag/Conjugate Unconjugated
Original Item Name Calcineurin Autoinhibitory Peptide
Molecule Name Calcineurin Autoinhibitory Peptide
Category Peptide
Unit 0.5 mg
Description Corresponds to a C-terminal domain (residues 457-482) of the calmodulin-binding domain of Calcineurin. Specific Calcineurin inhibitor. Does not inhibit CaM kinase II. protein phosphatase I or 2A. Inhibits Mn2+-stimulated calcineurin activity (IC50 = 10 mM using 32P myosin light chain as a substrate) but has no effect on Ni2+-stimulated activity. MW: 29304 Storage: 4°C for short term (weeks) and -20°C for long term. Stability: 6-12 months at -20°C. Sequence (One Letter Code): ITSFEEAKGLDRINERMPPRRDAMPSequence: {ILE} {THR} {SER} {PHE} {GLU} {GLU} {ALA} {LYS} {GLY} {LEU} {ASP} {ARG} {ILE} {ASN} {GLU} {ARG} {MET} {PRO} {PRO} {ARG} {ARG} {ASP} {ALA} {MET} {PRO} Formula: C124H205N39O39S2 Solubility: Soluble in water.