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Target/Molecule Synonym Interleukin 8
Species Equine
Target Tag/Conjugate Unconjugated
Format Purity: >95% by SDS PAGE analysis
Format: Purified recombinant protein - lyophilised
Molecule Name INTERLEUKIN-8
References [1] Dias. I. H. Marshall. L. Lambert. P. A. Chapple. I. L. Matthews. J. B. and Griffiths. H. R.
Gingipains from Porphyromonas gingivalis increase the chemotactic and respiratory burst-priming properties of the 77-amino-acid interleukin-8 variant
[2] Pioli. P. A. Jensen. A. L. Weaver. L. K. Amiel. E. Shen. Z. Shen. L. Wira. C. R. and Guyre. P. M.
Estradiol attenuates lipopolysaccharide-induced CXC chemokine ligand 8 production by human peripheral blood monocytes
[3] Yao. C. Lin. Y. Ye. C. S. Bi. J. Zhu. Y. F. and Wang. S. M. et al.
Role of interleukin-8 in the progression of estrogen receptor-negative breast cancer
[4] Yan. Y. Zhan. W. Zhao. G. Ma. J. and Cai. S. et al.
Use of SiRNA to investigate the role of CagA on H. pylori induced IL-8 production from gastric epithelial cells
[5] Abou-Shousha. S. Abd El-Megeed. M. H. and Sultan. H. K. et al.
Interleukin-8. ferritin and soluble transferrin receptors in type II diabetes mellitus
Accession Number Accession Number: NP_000575.1
Category Protein
Applications Functional Studies
Source/Expression System Recombinant
Unit 0.02 mg
Description Summary: The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant. and is also a potent angiogenic factor. This protein is believed to play a role in the pathogenesis of bronchiolitis. a common respiratory tract disease caused by viral infection. This protein and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. Sequence Length (aa): 99 KEGG pathway: Cytokine-cytokine receptor interaction 04060KEGG pathway: Epithelial cell signaling in Helicobacter pylori infection 05120KEGG pathway: Leukocyte transendothelial migration 04670KEGG pathway: Toll-like receptor signaling pathway 04620 OMIM: NCBI [ 146930] Applications Tested: FN Cross-Reactivity: Horse Storage: Prior to reconstitution store at +4C.Following reconstitution store at -70C.Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should Stability: 12 months from date of reconstitution. Specificity: IL-8 Specificity: IL-8 Preparation: Recombinant protein expressed in pichia pastorisPreservative Stabilisers: None presentReconstitution: Reconstitute with 0.5 ml distilled water.Buffer Solution: Phosphate buffered saline Product ID: 79011