Mouse Anti-COX-2 Monoclonal antibody, Unconjugated, Clone cox 229

  • Mouse Anti-COX-2 Monoclonal antibody, Unconjugated, Clone cox 229

    CatalogueID : 187379

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Target COX-2
Clone Clone cox 229
Target Species Mus musculus
Unit 0.5 ml
Description This antibody reacts specifically with COX-2 protein. Cyclooxygenase (COX) is a membrane-bound enzyme, which has a molecular weight of 72 kDa. It is an enzyme that catalyzes the synthesis of cyclic endoperoxides from arachidonic acid to form prostaglandins (lipid-soluble, homone-like regulatory molecules). Two isoforms of COX have been identified and are known as COX-1 and COX-2. COX-2 is dimeric and is the inducible (i.e., sites of inflammation) isoform of cyclooxygenase.Positive tissue: Colon carcinoma. Clone/PAD: COX 229 Immunogen: Synthetic peptide from human COX-2 Specificity: COX-2 Reactivity: Human Applications: Immunohistochemistry (FFPE) Pretreatment: Epitope Retrieval: Required (Citrate Buffer, pH 6.0), Enzyme Digestion: Not required Expected Staining Pattern: Cytoplasm
Clonality Monoclonal