Mouse Anti-CYTOKERATIN Monoclonal antibody, Unconjugated, Clone ae1...

  • Mouse Anti-CYTOKERATIN Monoclonal antibody, Unconjugated, Clone ae1/ae3

    CatalogueID : 180132

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Target Cytokeratin
Clone Clone ae1/ae3
Target Species Mus musculus
Unit 100 ug
Description This monoclonal antibody cocktail reacts with a broad range of cytokeratins. AE1 recognizes cytokeratins 10, 14, 15, 16, and 19 in the acidic subfamily. AE3 recognizes the entire basic subfamily of cytokeratins. The broad specificity of AE1/AE3 makes it useful for visualizing normal simple and neoplastic epithelial cells. It is an essential component of the antibody panel to screen for neoplasms of epithelial origin and to distinguish epithelial neoplasms from melanoma and lymphoma. Positive tissue: Skin. Clone/PAD: AE1/AE3 Immunogen: Human epidermal keratin Specificity: This antibody recognize 56.5, 50, 50' 48, and 40 kD keratins of the acidic subfamily and all members of the basic family. It shows no cross-reactivity to other filament types, including vimentin, desmin. Reactivity: Human Applications: Immunohistochemistry (FFPE) Pretreatment: Epitope Retrieval: Required (Citrate Buffer, pH 6.0) OR Enzyme Digestion: Required (Digest-Allâ„¢ 3/Pepsin)
Clonality Monoclonal