Mouse Anti-GCTM2 Monoclonal antibody, Unconjugated

  • Mouse Anti-GCTM2 Monoclonal antibody, Unconjugated

    CatalogueID : 433140

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Target GCTM2
Target Species Mus musculus
Unit 6 ml
Description Mouse anti-GCTM2; Antibody specific to Human and Baboon GCTM2. This antibody is validated for Western Blotting, IP, ICC, IHC, and Flow Cytometry. Anti-GCTM2 recognizes an epitope on a 200 kDa protein on the surface of embryonal carcinoma cells. Human embryonal carcinoma cell lysates were used to inject mice and generate monoclonal antibodies. Four different hybridomas were characterized. GCTM-1 stained the nuclei of all human cells tested. GCTM-2 recognized an epitope on a 200 kDa extracellular protein present on the surface of embryonal carcinoma cells, and stained the surface of visceral yolk sac-type carcinoma and colorectal carcinoma cells. Further analysis revealed that the antigen was a keratin sulphate proteoglycan. Two additional hybridomas, GCTM-3 and GCTM-4, were also generated from this fusion having distinctive staining patterns. GCTM-2 also stains tissue sections from human non-seminomatous germ cell tumours, and from seminomas. Fetal gut epithelium and muscle display
Clonality Monoclonal