Mouse Anti-Human CD39 Monoclonal antibody, Alexa fluor® ...

  • Mouse Anti-Human CD39 Monoclonal antibody, Alexa fluor® 488 Conjugated, Clone 143

    CatalogueID : MHCD3920

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Target CD39
Host Species Homo sapiens
Clone Clone 143
Target Species Mus musculus
Unit 100 tests
Description According to the literature, this antibody recognizes CD39, also known as ecto-nucleotidase (NTDPase1), an ADPase and ATPase found on the surface of endothelial cells, normal lymphocytes, and other leukocytes. It is strongly expressed on peripheral B-lymphocytes and is also expressed on subsets of T-cells and dendritic cells.2-5 CD39 appears to modulate platelet activation, cytokine effects, inflammatory responses, and cell-cell adhesion through its nucelotidase activity.4 CD39 has recently been found on regulatory T-cells, where it may facilitate T-reg function in areas of active inflammation that may have high concentrations of ATP. CD39 expression appears to segment the FoxP3-positive population.6
Clonality Monoclonal
Uniprot ID P49961