Mouse Anti-Human GAPDH Monoclonal antibody, Unconjugated, Clone 258

  • Mouse Anti-Human GAPDH Monoclonal antibody, Unconjugated, Clone 258

    CatalogueID : 437000
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Target GAPDH
Host Species Homo sapiens
Clone Clone 258
Target Species Mus musculus
Unit 50 ul
Description GAPDH (glyceraldehyde-3-phosphate dehydrogenase) is one of the key enzymes involved in glycolysis. It catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD).1 The enzyme exists as a tetramer of identical chains. Besides functioning as a glycolytic enzyme in cytoplasm, recent evidence suggests that mammalian GAPDH is also involved in a great number of intracellular processes such as membrane fusion, microtubule bundling, phosphotransferase activity, nuclear RNA export, DNA replication, and DNA repair.2 Since it is constitutively and stably expressed in almost all tissues at high level, GAPDH became a well-established house-keeping protein and is widely used as a loading control for protein normalization.
Clonality Monoclonal
Uniprot ID P04406