Mouse Anti-Human OxPhos Complex IV Subunit II Monoclonal Antibody, ...

  • Mouse Anti-Human OxPhos Complex IV Subunit II Monoclonal Antibody, Unconjugated, Clone 12C4

    CatalogueID : A6404

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Target OxPhos Complex IV Subunit II
Host Species Homo sapiens
Clone Clone 12C4
Target Species Mus musculus
Unit 100 ul
Description Complex IV subunit II monoclonal antibody is reactive to human. This antibody is validated for use in Western blotting and Immunocytochemistry . Cytochrome c oxidase is the fourth complex in the respiratory chain and is responsible for catalyzing the conversion of O2 to H2O. Subunit 2 of the cytochrome c oxidase complex combines with two other subunits (1 and 3) to form a core protein structure that performs many functions of the enzyme. The metallic copper center of this subunit transfers electrons to the heme center of subunit 1, which results in the movement of electrons from cytochrome c to the heme A3 and copper B metallic center of complex IV. Defects in subunit 2 of cytochrome c oxidase can result in COX deficiency, which may cause a wide range of symptoms that begin between infancy and adulthood. Abnormalities in this subunit are also associated with tumor development.
Clonality Monoclonal