Mouse Anti-Human TFP (Mitochondrial Trifunctional Protein) Monoclon...

  • Mouse Anti-Human TFP (Mitochondrial Trifunctional Protein) Monoclonal antibody, Unconjugated, Clone 2c2aa5

    CatalogueID : 459180

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Target TFP
Host Species Homo sapiens
Clone Clone 2c2aa5
Target Species Mus musculus
Unit 250 ul
Description Mouse Monoclonal antibody anti Mitochondrial Trifunctional Protein (TFP) monoclonal antibody (Sku 459180) is reactive against human protein, and is validated in Western blotting, and Immunocapture applications. TFP is part of the mitochondrial fatty acid beta-oxidation pathway. It is located in the inner mitochondrial membrane and it catalyzes three out of the four steps in the beta-oxidation cycle with a specific affinity for long chain substrates. TFP is a hetero-octamer composed of four a and four β-subunits. The α-subunit is a 79 kDa enzyme which has two enzymatic functions, the hydration of enoyl-CoA (E.C. and the dehydrogenation of 3-hydroxyacyl CoA (LCHAD - E.C. The β-subunit, a 47 kDa enzyme, performs the third function - the thiolytic cleavage of 3-ketoacyl-CoA substrates (E.C. Inherited deficiency of TFP is a recessive genetic disease which occurs in approximately 1:38,000 newborns in the US.
Clonality Monoclonal
Uniprot ID Q9HCM9