Mouse Anti-Human Thymidylate Synthase (Cocktail) Monoclonal Antibod...

  • Mouse Anti-Human Thymidylate Synthase (Cocktail) Monoclonal Antibody, Unconjugated, Clone TS106/4H4B1

    CatalogueID : 180405

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Target Thymidylate synthase
Host Species Homo sapiens
Clone Clone TS106/4H4B1
Target Species Mus musculus
Unit 0.5 ml
Description Thymidylate Synthase (TS) catalyzes the reductive methylation of dUMP by 5,10-methylene tetrahydrofolate to generate thymidylate and dihydrofolate. TS is a critical target enzyme in cancer chemotherapy. It has been reported that IHC expression of TS could assist in predicting response of colorectal cancer patients to modulated MTX-5-FU therapy. Positive tissue: Colon cancer/Breast cancer. Clone/PAD: TS106/4H4B1 Immunogen: Recombinant human thymidylate synthase protein Specificity: Thymidylate Synthase (TS) Reactivity: Human Applications: Immunohistochemistry (FFPE) Pretreatment: Epitope Retrieval: Required (EDTA, pH 8.0), Enzyme Digestion: Not Required Expected Staining Pattern: Nuclear and cytoplasmic
Clonality Monoclonal
Uniprot ID P04818