Mouse Anti-Mouse A2B5 Monoclonal antibody, Unconjugated

  • Mouse Anti-Mouse A2B5 Monoclonal antibody, Unconjugated

    CatalogueID : 433110

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Target A2B5
Host Species Mus musculus
Target Species Mus musculus
Unit 100 ug
Description Mouse anti-A2B5; Monoclonal antibody specific to Human, Chicken, Monkey (Rhesus), Mouse, Rat, Dog, Rabbit A2B5. This antibody is validated for use in Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, and Flow Cytometry. Antibody A2B5 was generated by immunizing mice with chicken embryo retina cells. This antibody binds to neural tissue such as retina, brain, spinal cord, and dorsal root ganglia. It is also able to bind plasma membranes of human, rat, chicken and mouse islet cells and can be used in cell sorting. A more detailed analysis of the antigen recognized by A2B5 showed that it is recognizing ganglioside GQ1c (but not GQ1b, nor other glycolipids such as GM1, GD1a, GD1b, GT1a, GT1b and GA1). This ganglioside marker has also been utilized in recognition of putative oligodendrocyte progenitor cells and A2B5-positive astrocytes in adult human white matter.
Clonality Monoclonal