Mouse Anti-RHEB Monoclonal antibody, Unconjugated, Clone 152

  • Mouse Anti-RHEB Monoclonal antibody, Unconjugated, Clone 152

    CatalogueID : 433210

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Target Rheb
Clone Clone 152
Target Species Mus musculus
Unit 100 ul
Description Mouse anti-RHEB (Sku 433210) detects Ras homolog enriched in brain (RHEB), which is the member of small GTPase superfamily, and involved in many cell signaling pathways such as mTor, raf and insulin. Its reactivity is confirmed in human, mouse and rat, with western blot, and based on sequence homology reactivity in chimpanzee, rhesus monkey, bovine and chicken is also expected. RHEB, Ras homolog enriched in brain, belongs to the small GTPase superfamily. It is ubiquitously expressed with highest levels expressed in skeletal and cardiac muscle. Like other family members, RHEB interacts with Raf-1 kinase and triggers activation of Raf-MEK-MAPK pathway. Mammalian target of rapamycin, mTOR, is a central regulator of cell growth. mTOR is a serine/threonine kinase that acts as a sensor for ATP and amino acids. Its activity is regulated by RHEB in response to growth factor stimulation and nutrient availability.
Clonality Monoclonal