Mouse Anti-TS (Thymidylate Synthase) Monoclonal antibody, Unconjuga...

  • Mouse Anti-TS (Thymidylate Synthase) Monoclonal antibody, Unconjugated, Clone 4h4b1

    CatalogueID : 180399

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Target TS
Clone Clone 4h4b1
Target Species Mus musculus
Unit 100 ug
Description Thymidylate Synthase (TS) catalyzes the reductive methylation of dUMP by 5,10-methylene tetrahydrofolate to generate thymidylate and dihydrofolate. TS is a critical target enzyme in cancer chemotherapy. It has been reported that IHC expression of TS could assist in predicting response of colorectal cancer patients to modulated MTX-5-FU therapy. Positive tissue: Colon cancer/Breast cancer. Clone/PAD: 4H4B1 Immunogen: Recombinant fusion protein of human thymidylate synthase. Specificity: Thymidylate Synthase (TS) Reactivity: Human Applications: Immunohistochemistry (FFPE) Pretreatment: Epitope Retrieval: Required (EDTA, pH 8.0), Enzyme Digestion: Not Required Expected Staining Pattern: Nuclear and cytoplasmic
Clonality Monoclonal