Mouse Anti-Tubulin, Alpha beta III Monoclonal antibody, Unconjugate...

  • Mouse Anti-Tubulin, Alpha beta III Monoclonal antibody, Unconjugated, Clone 38f4

    CatalogueID : 480011

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Target Tubulin Alpha beta III
Clone Clone 38f4
Target Species Mus musculus
Unit 500 ug
Description Tubulin, beta III, Mouse Monoclonal Antibody (SKU 480011) specific to Rat. This antibody is validated for use in WB and IHC. Tubulin, beta III, Mouse Monoclonal Antibody recognizes the expressed product of the Tubb3 gene, also known as MC1R, TUBB4, beta-4, TUBB3. Tubulin is the major constituent of microtubules, existing as a heterodimer of the a and b subunits. The beta III isoform of tubulin is found almost exclusively in neuronal processes of adult tissues and is therefore an excellent marker for neurons. Neuron specific, posttranslational modifications within the C-terminal domain of beta III tubulin have been shown to be developmentally regulated suggesting that they may serve to modulate the interaction of tubulin with microtubule associated proteins. Additionally, beta III tubulin has been found to be highly expressed in cancer cells such as small cell lung cancer, large cell neuroendocrine carcinoma and adenocarcinomas and is correlated with an increasing histological degree of malignancy.
Clonality Monoclonal