Rabbit Anti-AF-6 Abfinityâ„¢ Monoclonal Antibody , Unconjugated

  • Rabbit Anti-AF-6 Abfinityâ„¢ Monoclonal Antibody , Unconjugated

    CatalogueID : 700026

  • Contact Vendor

Unit 100 ug
Description ABfinityâ„¢ Recombinant Rabbit Monoclonal Antibody validated to Human and expected reactivity with human, mouse, rat, primates, sheep, equine, swine, bovine, canine, Xenopus. This antibody is validated for use in Immunofluorescence and Flow Cytometry. IRAK4 is encoded by the 51135 gene, also known as Interleukin-1 receptor-associated kinase 4, IPD1, REN64, NY-REN-64. Interleukin-1 receptor-associated kinases (IRAKs) are important mediators in the signal transduction of the Toll/IL-1 receptor (TIR) family. Members of the TIL family play a role in innate immune responses by coordinating host defense mechanisms. IRAK4 has been shown to interact with IRAK1 and TRAF6 in an IL-1-dependent manner, and overexpression of IRAK4 has been shown to activate NF?B as well as mitogen-activated protein (MAP) kinase pathways (1).