Rabbit Anti-Claudin 3 Polyclonal antibody, Unconjugated, Clone z23.jm

  • Rabbit Anti-Claudin 3 Polyclonal antibody, Unconjugated, Clone z23.jm

    CatalogueID : 187340

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Target Claudin 3
Clone Clone z23.jm
Target Species Oryctolagus cuniculus
Unit 100 ug
Description Tight junctions are specialized regions of cell-cell contact that are particularly abundant in luminal epithelial cell sheets. A study showed that Claudin-3 was found to be present or secreted by many of the genes up-regulated in ovarian cancer. Furthermore, in a recent study Claudin-3 expression was shown capable of mediating Clostridium perfringens enterotoxin (CPE) binding and cytolysis; this suggests that Claudin-3 could be a potential therapeutic strategy for prostate cancer. Positive tissue: Colon. Clone/PAD: Z23.JM Immunogen: A synthetic peptide from the C-terminus of mouse Claudin-3 Specificity: Claudin-3 Reactivity: Human, Mouse Applications: Immunohistochemistry (FFPE) Pretreatment: Epitope Retrieval: Required (Citrate buffer, pH 6.0), Enzyme Digestion: Not Required Expected Staining Pattern: Predominately membrane staining. Certain cancer tissues show cytoplasmic staining in addition to membrane staining.
Clonality Polyclonal