Rabbit Anti-Claudin-18 Abfinityâ„¢ Monoclonal Anti...

  • Rabbit Anti-Claudin-18 Abfinityâ„¢ Monoclonal Antibody , Unconjugated

    CatalogueID : 700059

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Target Claudin-18
Target Species Oryctolagus cuniculus
Unit 500 ug
Description ABfinity™ Recombinant Rabbit Monoclonal Antibody validated to Human and expected reactivity with human, chimpanzee, rhesus monkey, mouse, rat, horse, dog, and bovine. This antibody is validated for use in Western Blot, Immunohistochemistry, Immunofluorescence, and Flow Cytometry. T-bet is encoded by the 30009 gene, also known as T-box transcription factor TBX21, TBX21. T-bet, also known as TBX21, is a T-cell specific transcription factor containing a single T-box DNA-binding domain (1). It controls the expression of the TH1 cytokine, interferon-gamma. Both Th1 and Th17 cells are crucial in immune regulation and autoimmune disease development. T-bet initiates Th1 lineage development from naïve Th precursor cells and directs T cell differentiation to Th1 versus Th17 (2,3). T-bet is cooperating with Stat4 (signal tranducer and activator of transcription 4) in programming chromatin architecture for Th1 gene expression (4).
Clonality Monoclonal